Necrobiotic xanthogranuloma with paraproteinemia

Cutis. 1996 May;57(5):320-2.

Abstract

Necrobiotic xanthogranuloma (NXG) is a rare skin disease mimicking necrobiosis lipoidica diabeticorum clinically and histologically. However, its association with paraproteinemia, and the evolution of hematologic malignancies in some cases, established NXG as a separate clinicopathologic entity. A typical case with indolent course is described.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biopsy
  • Collagen / ultrastructure
  • Female
  • Foam Cells / pathology
  • Giant Cells / pathology
  • Humans
  • Necrobiosis Lipoidica / diagnosis*
  • Necrobiosis Lipoidica / pathology
  • Paraproteinemias / diagnosis*
  • Paraproteinemias / pathology
  • Skin / pathology
  • Xanthomatosis / diagnosis*
  • Xanthomatosis / pathology

Substances

  • Collagen