Shuttle-box memory facilitation by posttraining intracranial self-stimulation: differential effects in rats with high and low basic conditioning levels

Behav Neurosci. 1996 Apr;110(2):346-52. doi: 10.1037//0735-7044.110.2.346.

Abstract

The effects of intracranial self-stimulation (ICSS) on retention (after 24 hr, 7, 15, or 60 days) of a massed 2-way active avoidance task were studied in independent groups of rats. All groups showed a higher performance on the retention session than on the acquisition one. In the control subjects, the higher retention performances were observed in the 7- and 15-day groups. However, the ICSS treatment facilitated the 24-hr retention compared with its control group, allowing the treated subjects to achieve the same level of performance on the 24-hr retention session than that achieved by the control rats at the 7-day retention test. In the 24-hr groups, the facilitatory ICSS effect was stronger in the subjects with a low level of conditioning and weaker in those with a high level. Results suggest that posttraining ICSS accelerates memory consolidation and equalizes the performance of poor and good learners.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Avoidance Learning / physiology*
  • Brain Mapping
  • Conditioning, Classical / physiology*
  • Hypothalamic Area, Lateral / physiology*
  • Long-Term Potentiation / physiology
  • Male
  • Medial Forebrain Bundle / physiology
  • Mental Recall / physiology*
  • Motor Activity / physiology
  • Rats
  • Rats, Wistar
  • Reaction Time / physiology
  • Retention, Psychology / physiology*
  • Self Stimulation / physiology*