PET studies of the striatal dopaminergic system in Parkinson's disease (PD)

J Neural Transm Suppl. 1995:45:123-31.

Abstract

Positron emission tomography (PET) is a functional imaging technique which allows detection of biochemical and pharmacological dysfunction of the nigrostriatal dopaminergic system and provides the opportunity to investigate living patients with PD. This paper reviews the contribution of PET studies to the understanding of neurochemical changes underlying Parkinson's disease.

Publication types

  • Review

MeSH terms

  • Corpus Striatum / diagnostic imaging
  • Corpus Striatum / metabolism*
  • Dopamine / metabolism*
  • Humans
  • Parkinson Disease / diagnostic imaging
  • Parkinson Disease / metabolism*
  • Presynaptic Terminals / physiology
  • Receptors, Dopamine / metabolism
  • Substantia Nigra / diagnostic imaging
  • Substantia Nigra / metabolism
  • Synaptic Transmission / physiology
  • Tomography, Emission-Computed*

Substances

  • Receptors, Dopamine
  • Dopamine