Hepatocellular carcinoma complicating biliary cirrhosis caused by biliary atresia: report of a case

J Pediatr Surg. 1995 Dec;30(12):1713-6. doi: 10.1016/0022-3468(95)90461-1.

Abstract

A case of hepatocellular carcinoma complicating biliary cirrhosis caused by biliary atresia is reported. The patient had persistent severe jaundice with hepatosplenomegaly. A liver tumor was suspected because of the elevated serum alpha-fetoprotein and was shown by ultrasonography at 6 years of age. The tumor was treated with percutaneous ethanol injection therapy (PEIT). Nine months after initiation of PEIT, the patient died of massive bleeding from a metastatic tumor.

Publication types

  • Case Reports

MeSH terms

  • Biliary Atresia / complications*
  • Biliary Atresia / pathology
  • Biomarkers, Tumor / analysis
  • Carcinoma, Hepatocellular / etiology*
  • Carcinoma, Hepatocellular / pathology
  • Child, Preschool
  • Fatal Outcome
  • Female
  • Humans
  • Liver / pathology
  • Liver Cirrhosis / etiology*
  • Liver Cirrhosis / pathology
  • Liver Function Tests
  • Liver Neoplasms / etiology*
  • Liver Neoplasms / pathology
  • Palliative Care
  • alpha-Fetoproteins / analysis

Substances

  • Biomarkers, Tumor
  • alpha-Fetoproteins