In order to study the changes of the red-cell immunology, the rosette rates of the red cell C3b receptor (RBC-C3bRR) and red cell immune complex (RBC-ICR) were measured in 30 patients with laryngeal carcinoma. The results showed that: (1) the RBC-C3bRR and RBC-ICR were lower in patients with laryngeal carcinoma than those with polypus of the cord and the normal controls (P < 0.01); (2) the RBC-C3bRR and RBC-ICR of the patients with laryngeal carcinoma did not change in about twenty days after operation (P > 0.05). The results suggest that the red-cell immunological function is lowered in the patients with laryngeal carcinoma.