Abstract
PUVA-induced acrobullous dermatosis is characterized by the occurrence of blisters on the acral extremities during PUVA therapy. The tense blisters apparently arise as a result of PUVA damage to the epidermodermal cohesion coupled with friction or trauma. They must be distinguished from phototoxic reactions induced either by UVA over-dosage or excessive psoralen uptake. We report on, two cases of acrobullous PUVA-induced dermatosis, discussing clinical features, pathophysiological aspects and differential diagnosis.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Diagnosis, Differential
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Drug Eruptions / diagnosis*
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Drug Eruptions / pathology
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Female
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Fluorescent Antibody Technique, Indirect
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Foot Dermatoses / chemically induced*
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Foot Dermatoses / pathology
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Humans
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Male
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Middle Aged
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PUVA Therapy / adverse effects*
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Parapsoriasis / drug therapy*
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Parapsoriasis / pathology
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Psoriasis / drug therapy*
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Psoriasis / pathology
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Skin / drug effects
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Skin / pathology
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Skin Diseases, Vesiculobullous / chemically induced*
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Skin Diseases, Vesiculobullous / pathology