Bioactive polyacetylenes from Bidens pilosa

Planta Med. 1996 Aug;62(4):355-7. doi: 10.1055/s-2006-957902.

Abstract

From the methanolic extract of the whole plants of Bidens pilosa the new beta-D-glucopyranosyloxy-3-hydroxy-6(E)-tetradecen-8, 10,12-triyne besides a known polyine has been isolated and identified mainly by IR and NMR methods. The new compound showed overgrowing action against normal and transformed human cell lines in culture.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry*
  • Alkynes / isolation & purification
  • Alkynes / pharmacology
  • Animals
  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology
  • Antineoplastic Agents, Phytogenic / chemistry*
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / toxicity
  • Bacteria / drug effects
  • Cell Line
  • Cell Survival / drug effects
  • Glucosides / chemistry*
  • Glucosides / isolation & purification
  • Glucosides / pharmacology
  • Humans
  • Insecticides / chemistry*
  • Insecticides / isolation & purification
  • KB Cells
  • Larva
  • Leukemia P388
  • Magnetic Resonance Spectroscopy
  • Medicine, Traditional
  • Mexico
  • Mice
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Plant Extracts
  • Plants, Medicinal*
  • Spectrophotometry, Infrared
  • Spodoptera
  • Tumor Cells, Cultured

Substances

  • Alkynes
  • Anti-Bacterial Agents
  • Antineoplastic Agents, Phytogenic
  • Glucosides
  • Insecticides
  • Plant Extracts