High complication rates with pelvic allografts. Experience of 22 sarcoma resections

Acta Orthop Scand. 1996 Aug;67(4):333-8. doi: 10.3109/17453679609002326.

Abstract

We performed 22 reconstructions by allografts in patients with pelvic sarcoma: 14 Ewing's sarcomas, 7 chondrosarcomas, and 1 osteosarcoma. All patients with Ewing's sarcoma and osteosarcoma received chemotherapy. No patients with chondrosarcoma had adjuvant treatment. 12 reconstructions were iliosacral arthrodesis after resection of an ilium tumor, 1 was iliofemoral arthrodesis and 9 were pelvic reconstructions with total hip prosthesis after resection of an acetabulum tumor. In the surviving patients, the mean length of follow-up was 4 (2-6) years. 2 allografts fractured and 8 allografts developed an infection. The infection was commoner in patients who had chondrosarcomas, large tumors, and a long operation time. Neither chemotherapy nor radiotherapy increased the infection rate. All infected allografts had to be removed.

MeSH terms

  • Adolescent
  • Adult
  • Arthrodesis
  • Bone Neoplasms / drug therapy
  • Bone Neoplasms / surgery*
  • Bone Transplantation
  • Chemotherapy, Adjuvant
  • Child
  • Chondrosarcoma / surgery*
  • Female
  • Fractures, Bone
  • Humans
  • Male
  • Middle Aged
  • Pelvic Bones / surgery*
  • Postoperative Complications / etiology*
  • Sarcoma, Ewing / drug therapy
  • Sarcoma, Ewing / surgery*
  • Surgical Wound Infection / surgery
  • Transplantation, Homologous
  • Treatment Outcome