Studies on the formation of hepatic DNA adducts by the antiandrogenic and gestagenic drug, cyproterone acetate: 1. adduct levels in various species including man and 2. persistence and accumulation in the rat

Adv Exp Med Biol. 1996:387:253-7. doi: 10.1007/978-1-4757-9480-9_33.
No abstract available

MeSH terms

  • Androgen Antagonists / metabolism*
  • Androgen Antagonists / toxicity*
  • Animals
  • Cells, Cultured
  • Cyproterone Acetate / metabolism*
  • Cyproterone Acetate / toxicity*
  • DNA Adducts / metabolism*
  • DNA Fingerprinting
  • Female
  • Hormone Antagonists / metabolism*
  • Hormone Antagonists / toxicity*
  • Humans
  • Liver / drug effects
  • Liver / metabolism*
  • Male
  • Rats
  • Rats, Wistar
  • Swine

Substances

  • Androgen Antagonists
  • DNA Adducts
  • Hormone Antagonists
  • Cyproterone Acetate