Abstract
The susceptibilities of 50 unique vancomycin-susceptible (n = 15) and vancomycin-resistant (n = 35) enterococci to 6 antimicrobials were compared. Teicoplanin was consistently the most active agent for all strains. Ampicillin and imipenem were active primarily for vancomycin-sensitive Enterococcus faecalis. Clinafloxacin and ciprofloxacin showed poorer activity compared to prior studies, suggesting that the emergence of quinolone resistance is now occurring in enterococci.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Ampicillin / pharmacology
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Anti-Bacterial Agents / pharmacology*
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Anti-Infective Agents / pharmacology*
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Ciprofloxacin / pharmacology
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Drug Resistance, Microbial
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Enterococcus / drug effects*
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Enterococcus faecalis / drug effects
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Enterococcus faecium / drug effects
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Fluoroquinolones*
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Imipenem / pharmacology
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Microbial Sensitivity Tests
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Penicillins / pharmacology
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Quinolones / pharmacology*
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Teicoplanin / pharmacology
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Thienamycins / pharmacology
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Vancomycin / pharmacology*
Substances
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Anti-Bacterial Agents
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Anti-Infective Agents
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Fluoroquinolones
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Penicillins
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Quinolones
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Thienamycins
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Ciprofloxacin
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Teicoplanin
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Vancomycin
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Imipenem
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Ampicillin
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clinafloxacin