A tangential neuronal migration in the olfactory bulbs of adult lizards

Neuroreport. 1996 May 17;7(7):1257-60. doi: 10.1097/00001756-199605170-00007.

Abstract

Tritiated thymidine ([3H]thymidine) autoradiography at different times after experiments showed that postnatally generated neurones in the adult lizard olfactory bulbs are not generated in a local germinative zone but in the ventricular zone (VZ) of the cerebral hemispheres, which is a long distance from the olfactory bulbs. The new cells originating in the VZ of rostral telencephalon migrate to both main and accessory olfactory bulbs through the olfactory peduncle, along a highly restricted pathway orthogonal to the orientation of radial glial fibres. Our results suggest that the olfactory bulb interneurones of adult lizards may follow a tangential migration route from their germinative zone, as is the case in mammals.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Autoradiography
  • Brain Mapping*
  • Cell Count
  • Cell Movement / physiology
  • Cell Survival / physiology
  • Ependyma / cytology*
  • Lizards / anatomy & histology*
  • Neurons / cytology*
  • Olfactory Bulb / cytology*
  • Telencephalon / cytology*