Abstract
Upon the addition of beta-lactam antibiotics at concentrations that caused a 50% reduction in the dry weight, beta-haemolytic streptococci produced increased amount of rhamnose, though the hexosamine content remained unchanged. These sugars are components of C-carbohydrate. Sialic acid content also increased in group B streptococcal surfaces and penicillin treatment generated new accessible surface sialic acid residues.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Anions
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Anti-Bacterial Agents / pharmacology*
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Carbohydrate Metabolism*
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Hexosamines / metabolism
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Rhamnose / metabolism
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Sialic Acids / metabolism
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Streptococcus agalactiae / drug effects*
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Streptococcus agalactiae / metabolism*
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Surface Properties
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beta-Lactams
Substances
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Anions
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Anti-Bacterial Agents
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Hexosamines
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Sialic Acids
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beta-Lactams
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Rhamnose