Abstract
Rhodococcus equi is emerging as a cause of pneumonia in immunocompromised people, especially those with AIDS. Like mycobacteria, R. equi is phagocytosed by alveolar macrophages and replicates within them. Recent work is beginning to elucidate the cell and molecular biology of this opportunistic pathogen and the host immune response to it.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Actinomycetales Infections* / epidemiology
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Actinomycetales Infections* / immunology
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Actinomycetales Infections* / microbiology
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Animals
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Humans
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Opportunistic Infections* / epidemiology
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Opportunistic Infections* / immunology
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Opportunistic Infections* / microbiology
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Pneumonia / epidemiology
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Pneumonia / immunology
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Pneumonia / microbiology
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Rhodococcus equi* / classification
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Rhodococcus equi* / immunology
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Rhodococcus equi* / pathogenicity
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Virulence