Analysis of mortality rates via marginal extended quasi-likelihood

Stat Med. 1996 Jul 15;15(13):1397-407. doi: 10.1002/(SICI)1097-0258(19960715)15:13<1397::AID-SIM272>3.0.CO;2-6.

Abstract

We use a mixed Poisson regression model with extra variation to analyse mortality data cross-classified by age and geographic region. We use estimates of dispersion parameter and fixed effects parameters, obtained by maximizing a marginal quasi-likelihood function, to estimate mortality rates in an empirical Bayes manner. This is a modification of an earlier method by Tsutakawa that used the likelihood function and is computationally impractical for routine use. In order to apply the extended quasi-likelihood function, a linear variance function (of the mean) is used in place of a quadratic one used previously. We illustrate the method with male lung cancer deaths in the state of Missouri.

MeSH terms

  • Age Distribution
  • Bayes Theorem
  • Bias
  • Humans
  • Likelihood Functions*
  • Linear Models
  • Lung Neoplasms / mortality
  • Male
  • Missouri / epidemiology
  • Mortality*
  • Poisson Distribution
  • Reproducibility of Results
  • Residence Characteristics