Elevated maternal serum and amniotic fluid alpha-fetoprotein levels in the Denys-Drash syndrome

Prenat Diagn. 1996 May;16(5):455-7. doi: 10.1002/(SICI)1097-0223(199605)16:5<455::AID-PD865>3.0.CO;2-S.

Abstract

We report the findings in a child with the Denys-Drash syndrome presenting prenatally with a diaphragmatic hernia, male pseudohermaphroditism, and elevated alpha-fetoprotein levels i amniotic fluid and in maternal serum.

Publication types

  • Case Reports

MeSH terms

  • Amniocentesis
  • Amniotic Fluid / chemistry*
  • Disorders of Sex Development / genetics
  • Fatal Outcome
  • Female
  • Fetal Diseases / diagnosis*
  • Fetal Diseases / embryology
  • Fetal Diseases / genetics
  • Gestational Age
  • Hernia, Diaphragmatic / diagnostic imaging
  • Hernia, Diaphragmatic / embryology
  • Humans
  • Infant, Newborn
  • Kidney Neoplasms / genetics
  • Male
  • Nephrotic Syndrome / diagnosis*
  • Nephrotic Syndrome / embryology
  • Nephrotic Syndrome / genetics
  • Point Mutation / genetics
  • Pregnancy
  • Prenatal Diagnosis*
  • Ultrasonography, Prenatal
  • Wilms Tumor / genetics
  • alpha-Fetoproteins / analysis*

Substances

  • alpha-Fetoproteins