Aneurysm formation in modified human umbilical vein grafts

Eur J Vasc Endovasc Surg. 1996 May;11(4):417-20. doi: 10.1016/s1078-5884(96)80173-0.

Abstract

Objectives: Aneurysm formation in Human Umbilical Vein Grafts has been reported to be as high as 65% after 5 years. One of the causes might be the structure of the Biograft-wall and in 1985 a new method of processing the graft was begun. In Groningen this new improved Biograft has been used since late 1986.

Design: Duplex scanning was used to examine the frequency of aneurysm formation in the new improved Biograft.

Materials: Sixty-nine patent Biografts have been examined in a period up to 6 years after implantation.

Main results: Aneurysms were found in only 17% of grafts although the frequency increased with time. Dilatation was common but may be due to a more elastic graft.

Conclusion: These findings justify the continued use of the new Biograft as a substitute for arterial femoropopliteal reconstructions.

MeSH terms

  • Aged
  • Aneurysm / diagnostic imaging
  • Aneurysm / epidemiology
  • Aneurysm / etiology*
  • Blood Vessel Prosthesis*
  • Dilatation, Pathologic / diagnostic imaging
  • Dilatation, Pathologic / epidemiology
  • Dilatation, Pathologic / etiology
  • Female
  • Follow-Up Studies
  • Graft Occlusion, Vascular / diagnostic imaging
  • Graft Occlusion, Vascular / epidemiology
  • Graft Occlusion, Vascular / etiology*
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Prosthesis Design
  • Time Factors
  • Ultrasonography, Doppler, Duplex
  • Umbilical Veins / transplantation*