Phonologic processing deficits in Alzheimer's disease

Neurology. 1995 Dec;45(12):2165-9. doi: 10.1212/wnl.45.12.2165.

Abstract

We investigated phonologic production in patients with mild to moderate Alzheimer's disease (AD) on a repetition task. AD patients produced significantly more speech errors than age-matched controls. AD patients' errors, unlike those of controls, resulted in the transformation of real words into pseudowords, occurred disproportionately in word-initial positions, and were not influenced by the phonologic environment. This pattern of errors suggests a lexical phonologic retrieval deficit in AD.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / complications*
  • Humans
  • Middle Aged
  • Reference Values
  • Speech
  • Speech Disorders / etiology*
  • Speech Disorders / psychology