Abstract
Trinucleotide repeat expansions or unstable mutations are the cause of a growing number of hereditary movement disorders, especially inherited ataxias. Diagnostic practice as well as disease classifications have altered accordingly. Genes responsible for "Parkinsonian plus' syndromes and episodic movement disorders have also been recently mapped.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Chromosome Aberrations / genetics
-
Chromosome Disorders
-
DNA Mutational Analysis
-
Genotype
-
Humans
-
Movement Disorders / classification
-
Movement Disorders / diagnosis
-
Movement Disorders / genetics*
-
Parkinson Disease, Secondary / classification
-
Parkinson Disease, Secondary / diagnosis
-
Parkinson Disease, Secondary / genetics
-
Phenotype
-
Spinocerebellar Degenerations / classification
-
Spinocerebellar Degenerations / diagnosis
-
Spinocerebellar Degenerations / genetics
-
Trinucleotide Repeats / genetics