Diabetes mellitus in Kearns-Sayre syndrome: a case with a 10-year follow-up

Diabetes Res Clin Pract. 1995 Dec;30(3):233-5. doi: 10.1016/0168-8227(95)01187-0.

Abstract

An 11-year-old girl with Kearns-Sayre Syndrome developed diabetes mellitus with ketoacidosis at onset and immediate insulin-requirement. In a 10-year follow-up, while neuromuscular disease was progressively increasing, diabetes was well controlled by once-a-day insulin therapy. Insulin secretion appears low, but without impairment during the years. This case points out the diabetes' features in Kearns-Sayre syndrome.

Publication types

  • Case Reports

MeSH terms

  • Age of Onset
  • Child
  • Diabetes Mellitus, Type 1 / complications
  • Diabetes Mellitus, Type 1 / drug therapy
  • Diabetes Mellitus, Type 1 / physiopathology*
  • Female
  • Follow-Up Studies
  • Humans
  • Hypoglycemic Agents / pharmacology
  • Hypoglycemic Agents / therapeutic use
  • Insulin / pharmacology
  • Insulin / therapeutic use
  • Kearns-Sayre Syndrome / complications
  • Kearns-Sayre Syndrome / physiopathology*

Substances

  • Hypoglycemic Agents
  • Insulin