Screening study of abdominal aortic aneurysm in a general population: lipid parameters

Cardiovasc Surg. 1996 Aug;4(4):445-8. doi: 10.1016/0967-2109(95)00140-9.

Abstract

The level of blood lipids and apolipoproteins in subjects being screened for abdominal aortic aneurysms have been investigated. As part of an ultrasound screening programme in a population of 65- to 75-year-olds, blood samples were collected from 1460 of 1504 subjects with a normal aorta (97.1%) and 69 of 70 patients with an abdominal aortic aneurysm > 29 mm (99%). Samples were also taken from 22 of 27 patients (81%) with an ectatic aorta (26-29 mm). Total cholesterol, HDL-cholesterol, LDL-cholesterol, Apo-AI and Apo-B levels were significantly higher in women than in men (P < 0.01). Levels of HDL-cholesterol and Apo-AI were significantly lower in patients with an abdominal aortic aneurysm than in normal subjects (P < 0.001). The mean(s.d.) body mass index was 25.1(3.9) in women and 25.5(3.2) in men with aneurysms and not significantly greater than that of normal subjects (25.2(3.61) and 25.2(3.38) respectively).

MeSH terms

  • Aged
  • Aortic Aneurysm, Abdominal / blood
  • Aortic Aneurysm, Abdominal / diagnostic imaging
  • Aortic Aneurysm, Abdominal / prevention & control*
  • Apolipoprotein A-I / blood
  • Apolipoproteins / blood*
  • Apolipoproteins B / blood
  • Body Mass Index
  • Cholesterol / blood
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Female
  • Humans
  • Lipids / blood*
  • Male
  • Mass Screening*
  • Risk Factors
  • Sex Factors
  • Ultrasonography

Substances

  • Apolipoprotein A-I
  • Apolipoproteins
  • Apolipoproteins B
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Lipids
  • Cholesterol