Farnesyltransferase inhibitors: a new class of cancer chemotherapeutics

Biochem Soc Trans. 1996 Aug;24(3):688-92. doi: 10.1042/bst0240688.
No abstract available

Publication types

  • Review

MeSH terms

  • Alkyl and Aryl Transferases*
  • Amino Acid Sequence
  • Animals
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Farnesyltranstransferase
  • Humans
  • Models, Molecular
  • Molecular Structure
  • Oligopeptides / chemistry
  • Oligopeptides / pharmacology
  • Protein Conformation
  • Transferases / antagonists & inhibitors*
  • Transferases / chemistry
  • ras Proteins / chemistry
  • ras Proteins / metabolism

Substances

  • Antineoplastic Agents
  • Enzyme Inhibitors
  • Oligopeptides
  • cysteinyl-valyl-tryptophyl-methionine
  • Transferases
  • Alkyl and Aryl Transferases
  • geranylgeranyltransferase type-I
  • p21(ras) farnesyl-protein transferase
  • Farnesyltranstransferase
  • ras Proteins