Liquid chromatographic analysis of endogenous catecholamine release from brain slices

Science. 1977 Aug 26;197(4306):904-6. doi: 10.1126/science.887928.

Abstract

A simple new liquid chromatographic technique has been applied to transmitter release studies in brain slice preparations. This method, which gives direct readings of picomoles of endogenous transmitter released, has been shown to yield reliable results with a variety of brain slice manipulations.

MeSH terms

  • Amphetamine / pharmacology
  • Animals
  • Brain / metabolism*
  • Catecholamines / metabolism*
  • Chlorpromazine / pharmacology
  • Chromatography, High Pressure Liquid
  • Corpus Striatum / metabolism
  • Dopamine / metabolism
  • Electric Stimulation
  • Hypothalamus / metabolism
  • In Vitro Techniques
  • Methods
  • Norepinephrine / metabolism
  • Rats

Substances

  • Catecholamines
  • Amphetamine
  • Chlorpromazine
  • Dopamine
  • Norepinephrine