Abstract
The regulation of GH secretion involves finely balanced systems with multiple components. As our knowledge of the physiology of GH regulation expands, so does our understanding of the bases for GH diseases. We now can identify several cellular loci that cause GH deficiency or GH excess. In addition, the recent increased understanding of GH physiology has resulted in an increase in potential therapies for growth disorders.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Aging / physiology
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Feedback
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Growth / physiology
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Growth Hormone-Releasing Hormone / physiology
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Human Growth Hormone / deficiency
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Human Growth Hormone / metabolism*
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Human Growth Hormone / physiology
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Humans
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Hypothalamus / physiology
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Neurotransmitter Agents / physiology
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Pituitary Gland, Anterior / physiology
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Somatostatin / physiology
Substances
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Neurotransmitter Agents
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Human Growth Hormone
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Somatostatin
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Growth Hormone-Releasing Hormone