Abstract
A patient who had previously undergone resection of a malignant glioma followed by radiation therapy was found to have a focus of a high accumulation of thallous chloride Tl 201 on single-photon emission CT scans, suggesting recurrent tumor. Resection of this area was performed and the specimen showed radiation necrosis, including such reactive changes as reactive astrocytes and lymphocytes in the necrotic tissue. This case illustrates a diagnostic pitfall in the use of 201Tl single-photon emission CT for distinguishing radiation necrosis from recurrent tumor in patients treated for malignant glioma.
MeSH terms
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Brain Neoplasms / diagnostic imaging*
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Brain Neoplasms / pathology
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Brain Neoplasms / radiotherapy
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Brain Neoplasms / surgery
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Combined Modality Therapy
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Cranial Irradiation*
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Diagnosis, Differential
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Female
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Frontal Lobe / pathology
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Frontal Lobe / radiation effects*
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Frontal Lobe / surgery
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Ganglioglioma / diagnostic imaging*
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Ganglioglioma / pathology
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Ganglioglioma / radiotherapy
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Ganglioglioma / surgery
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Humans
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Middle Aged
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Necrosis
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Neoplasm Recurrence, Local / diagnostic imaging*
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Neoplasm Recurrence, Local / pathology
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Neoplasm Recurrence, Local / surgery
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Radiation Injuries / diagnostic imaging*
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Radiation Injuries / pathology
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Radiation Injuries / surgery
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Radionuclide Imaging
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Radiotherapy, Adjuvant