Abstract
Hepatitis C virus genotypes were determined for 358 viremic individuals in Montreal, Canada, by restriction endonuclease analysis of PCR products and phylogenetic analysis of core gene sequences. Types 1, 2, and 3 occurred in 62.8, 14.2, and 13.7%, respectively; types 4 and 5 were found in 3.9 and 4.5%, respectively; and genotypes 6a and 7c and a novel genotype each occurred in 0.3%. Types 4, 6, and 7 and the novel genotype were mostly from persons who had immigrated to Canada.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Emigration and Immigration
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Genotype
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Hepacivirus / classification
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Hepacivirus / genetics*
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Hepacivirus / isolation & purification*
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Hepatitis C / epidemiology
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Hepatitis C / virology
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Humans
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Middle Aged
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Molecular Epidemiology
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Molecular Sequence Data
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Phylogeny
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Polymerase Chain Reaction
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Quebec / epidemiology
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RNA, Viral / genetics
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Viremia / virology
Associated data
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GENBANK/U33430
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GENBANK/U33431
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GENBANK/U33432
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GENBANK/U33433
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GENBANK/U33434
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GENBANK/U33435
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GENBANK/U33436
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GENBANK/U33437
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GENBANK/U52810
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GENBANK/U52811