Comparison of the protective response induced by NYVAC vaccinia recombinants expressing either gp50 or gII and gp50 of pseudorabies virus

Can J Vet Res. 1996 Oct;60(4):315-7.

Abstract

A NYVAC vaccinia vector containing genes for pseudorables virus glycoproteins gII and gp50 was administered to pigs to determine if it would have a greater protective effect than a vector containing the gene for gp50 alone. Both NYVAC vectors protected pigs similarly from virulent pseudorabies virus challenge.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Antibodies, Viral / immunology
  • Antibodies, Viral / metabolism*
  • Body Temperature / physiology
  • Body Weight / physiology
  • Genetic Vectors
  • Herpesvirus 1, Suid / immunology*
  • Herpesvirus 1, Suid / metabolism
  • Male
  • Pseudorabies / immunology
  • Pseudorabies / physiopathology
  • Pseudorabies / prevention & control*
  • Swine / immunology*
  • Swine / metabolism
  • Swine / physiology
  • Swine Diseases / immunology
  • Swine Diseases / physiopathology
  • Swine Diseases / prevention & control*
  • Vaccines, Synthetic / genetics*
  • Vaccines, Synthetic / immunology
  • Vaccines, Synthetic / pharmacology*
  • Viral Fusion Proteins / genetics*
  • Viral Fusion Proteins / immunology*
  • Viral Fusion Proteins / metabolism

Substances

  • Antibodies, Viral
  • Vaccines, Synthetic
  • Viral Fusion Proteins