Transient neutropenia in a patient receiving cimetidine

Gastroenterology. 1977 Sep;73(3):635-8.

Abstract

Transient neutropenia developed in a 62-year-old, white male on maintenance hemodialysis being treated with cimetidine for an in tractable duodenal ulcer. The probable mechanism was peripheral destruction of the granulocyte series, unlike the marrow depression reported with metiamide, another histamine H2 receptor antagonist.

Publication types

  • Case Reports

MeSH terms

  • Agranulocytosis / chemically induced*
  • Anti-Ulcer Agents / adverse effects*
  • Anti-Ulcer Agents / therapeutic use
  • Duodenal Ulcer / drug therapy
  • Guanidines / adverse effects*
  • Guanidines / therapeutic use
  • Humans
  • Imidazoles / adverse effects*
  • Imidazoles / therapeutic use
  • Male
  • Middle Aged
  • Neutropenia / chemically induced*
  • Renal Dialysis

Substances

  • Anti-Ulcer Agents
  • Guanidines
  • Imidazoles