Abstract
Two children developed multiple melanocytic naevi after polychemotherapy administered for acute lymphoblastic leukaemia in one and for non-Hodgkin lymphoma in the other. Induction of naevi does not seem to be related to specific agents used in chemotherapy, but rather to the immunosuppression resulting from multiple-agent chemotherapy. There are reports in the literature of both intrinsically and iatrogenically immunosuppressed patients who have developed multiple melanocytic naevi.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / adverse effects*
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Child
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Female
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Humans
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Immune Tolerance / drug effects
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Immune Tolerance / immunology
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Lymphoma, T-Cell / drug therapy*
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Lymphoma, T-Cell / immunology
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Male
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Nevus, Pigmented / chemically induced*
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Nevus, Pigmented / immunology
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Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
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Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology
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Skin Neoplasms / chemically induced*
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Skin Neoplasms / immunology