Hypomelanosis of Ito and brain abnormalities: MRI findings and literature review

J Steiner; C Adamsbaum; I Desguerres; G Lalande; F Raynaud; G Ponsot; G Kalifa

doi:10.1007/BF01396196

Hypomelanosis of Ito and brain abnormalities: MRI findings and literature review

Pediatr Radiol. 1996 Nov;26(11):763-8. doi: 10.1007/BF01396196.

Authors

J Steiner¹, C Adamsbaum, I Desguerres, G Lalande, F Raynaud, G Ponsot, G Kalifa

Affiliation

¹ Service de Radiologie, Hôpital St. Vincent de Paul, 82 avenue Denfert Rochereau, F-75674 Paris Cedex 14, France.

PMID: 8929372
DOI: 10.1007/BF01396196

Abstract

We report the results of a 14-year retrospective study of brain MRI abnormalities in 12 pediatric patients presenting with hypomelanosis of Ito (HI). Miscellaneous brain abnormalities were found: one patient had a medulloblastoma, three had cortical malformations, and five demonstrated "minor" abnormalities such as dilated Virchow-Robin spaces or brain atrophy. We emphasize the polymorphism of brain abnormalities associated with HI.

Publication types

Review

MeSH terms

Adolescent
Atrophy
Brain / abnormalities*
Brain / pathology
Brain Neoplasms / complications
Brain Neoplasms / diagnosis
Cerebral Ventricles / pathology
Child
Child, Preschool
Dilatation, Pathologic / complications
Dilatation, Pathologic / diagnosis
Female
Humans
Hypertrophy
Hypopigmentation / complications
Infant
Magnetic Resonance Imaging*
Male
Medulloblastoma / complications
Medulloblastoma / diagnosis
Pigmentation Disorders / complications*
Polymorphism, Genetic
Retrospective Studies
Tomography, X-Ray Computed