Abstract
SpoIIAA is the first protein of the spoIIA operon. Here we show that SpoIIAA can bind and hydrolyze GTP. The protein also accepts ATP, but with lower affinity. GDP competes poorly for binding of GTP. The GTPase activity of SpoIIAA is within the range found for other GTP-binding proteins.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacillus subtilis / enzymology*
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Bacterial Proteins / classification
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Bacterial Proteins / drug effects
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Bacterial Proteins / metabolism*
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Bacterial Proteins / radiation effects
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Dose-Response Relationship, Drug
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GTP Phosphohydrolases / classification
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GTP Phosphohydrolases / drug effects
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GTP Phosphohydrolases / metabolism*
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GTP Phosphohydrolases / radiation effects
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GTP-Binding Proteins / classification
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GTP-Binding Proteins / drug effects
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GTP-Binding Proteins / metabolism*
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GTP-Binding Proteins / radiation effects
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Guanosine Diphosphate / metabolism
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Guanosine Triphosphate / metabolism*
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Guanosine Triphosphate / radiation effects
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Magnesium / pharmacology
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Sigma Factor*
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Transcription Factors*
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Ultraviolet Rays
Substances
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Bacterial Proteins
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Sigma Factor
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Transcription Factors
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spoIIR protein, Bacillus subtilis
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spore-specific proteins, Bacillus
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Guanosine Diphosphate
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Guanosine Triphosphate
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GTP Phosphohydrolases
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GTP-Binding Proteins
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Magnesium