Anthelmintic 2-arylhydrazino- and 2-arylazo-2-thiazolines

J Pharm Sci. 1977 Aug;66(8):1150-3. doi: 10.1002/jps.2600660826.

Abstract

Some 2-arylhydrazino- and 2-arylazo-2-thiazolines were synthesized for anthelmintic testing. The most potent compound, 2-(o-tolylazo)-2-thiazoline, was orally effective in sheep against a broad range of helminths.

MeSH terms

  • Animals
  • Anthelmintics / chemical synthesis*
  • Anthelmintics / therapeutic use
  • Helminthiasis / drug therapy
  • Methods
  • Sheep
  • Structure-Activity Relationship
  • Thiazoles / chemical synthesis*
  • Thiazoles / pharmacology
  • Thiazoles / therapeutic use

Substances

  • Anthelmintics
  • Thiazoles