RF catheter ablation is a safe and extremely effective method of achieving complete A-V block in patients with difficult-to-control ventricular rates in atrial fibrillation. In selected patients, A-V junction ablation may improve exercise capacity and functional status while reducing the need for emergency care and hospitalization. Prospective, randomized studies are needed, however, to compare A-V junction ablation as a management strategy to pharmacologic therapy to control ventricular rate or to maintain sinus rhythm. Similarly, additional data are needed to assess methods of achieving A-V junction modification with the lowest risk for A-V block.