Cyclosporine nephrotoxicity evaluated by tissue calcium deposition and tubular enzymes is prevented by L-propionylcarnitine in isolated perfused rat kidney

Transplant Proc. 1996 Dec;28(6):3122-5.
No abstract available

MeSH terms

  • Acetylglucosaminidase / metabolism
  • Analysis of Variance
  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Calcium / metabolism*
  • Carnitine / analogs & derivatives*
  • Carnitine / pharmacology
  • Cyclosporine / antagonists & inhibitors
  • Cyclosporine / toxicity*
  • Dose-Response Relationship, Drug
  • Immunosuppressive Agents / antagonists & inhibitors
  • Immunosuppressive Agents / toxicity*
  • In Vitro Techniques
  • Kidney / drug effects
  • Kidney / metabolism
  • Kidney / pathology*
  • Kidney Tubules / enzymology*
  • Male
  • Perfusion
  • Rats
  • Rats, Wistar

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Immunosuppressive Agents
  • propionylcarnitine
  • Cyclosporine
  • Acetylglucosaminidase
  • Carnitine
  • Calcium