Scanning electron microscopic studies on untreated and transformed mouse embryo fibroblast cell cultures

G Ferencz; B Szende; K Lapis; E Podmaniczky

doi:10.1016/s0014-4908(77)80013-6

Scanning electron microscopic studies on untreated and transformed mouse embryo fibroblast cell cultures

Exp Pathol (Jena). 1977;13(4-5):275-9. doi: 10.1016/s0014-4908(77)80013-6.

Authors

G Ferencz, B Szende, K Lapis, E Podmaniczky

PMID: 902709
DOI: 10.1016/s0014-4908(77)80013-6

Abstract

Cultures of CBA T6T6 mouse embryo cells were transformed by 20-methylcholanthrene (MC) treatment in vitro. Untreated and MC treated cells and reexplanted cells of tumours originating from MC treated cells were compared by scanning electron microscopy (SEM). The 3 cultures showed considerable differences in the situation of the cells compared to each other, as well as in the number and shape of the surface formations.

MeSH terms

Animals
Cell Transformation, Neoplastic / drug effects
Cells, Cultured
Fibroblasts / drug effects*
In Vitro Techniques
Methylcholanthrene / pharmacology*
Mice
Mice, Inbred CBA
Microscopy, Electron, Scanning

Substances

Methylcholanthrene