Current status of retinoids in chemoprevention of oral squamous cell carcinoma: an overview

J Craniomaxillofac Surg. 1996 Dec;24(6):339-45. doi: 10.1016/s1010-5182(96)80034-5.

Abstract

Squamous cell carcinoma of the oral cavity and oropharynx may be amenable to chemoprevention. This review focuses on current concepts of mechanisms in oral carcinogenesis, as well as the evidence that retinoids have a role in the primary and secondary prevention of this malignancy.

Publication types

  • Review

MeSH terms

  • Anticarcinogenic Agents / metabolism
  • Anticarcinogenic Agents / pharmacology
  • Anticarcinogenic Agents / therapeutic use*
  • Carcinoma, Squamous Cell / etiology
  • Carcinoma, Squamous Cell / prevention & control*
  • Chemoprevention
  • Humans
  • Leukoplakia, Oral / prevention & control
  • Mouth Neoplasms / etiology
  • Mouth Neoplasms / prevention & control*
  • Neoplasms, Second Primary / prevention & control
  • Oropharyngeal Neoplasms / etiology
  • Oropharyngeal Neoplasms / prevention & control
  • Retinoids / metabolism
  • Retinoids / pharmacology
  • Retinoids / therapeutic use*

Substances

  • Anticarcinogenic Agents
  • Retinoids