[Sensory Jacksonian seizures as initial manifestation of sarcoidosis]

Nervenarzt. 1996 Oct;67(10):883-5. doi: 10.1007/s001150050067.
[Article in German]

Abstract

A 46-year old patient is reported presenting with somatosensory focal seizures of either arm as the only manifestation of an otherwise clinically inapparent sarcoidosis. MRI showed signs of a granulomatous leptomeningeal affection. Histological examination of a meningeal biopsy proved the diagnosis of sarcoidosis by demonstrating noncaseating granulomas. There was no other clinical manifestation of sarcoidosis. Chest X-ray was normal and the serum level of angiotensin-converting-enzyme was only slightly elevated. The CD4/CD8 ratio in the bronchoalveolar lavage cell population, however, was clearly abnormal, supporting the role of this diagnostic tool in the diagnosis of sarcoidosis.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Biopsy
  • Brain Diseases / complications*
  • Brain Diseases / pathology
  • Bronchoalveolar Lavage Fluid / cytology
  • CD4-CD8 Ratio
  • Diagnosis, Differential
  • Epilepsies, Partial / etiology*
  • Epilepsies, Partial / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Meninges / pathology
  • Middle Aged
  • Sarcoidosis / complications*
  • Sarcoidosis / pathology
  • Sarcoidosis, Pulmonary / complications
  • Sarcoidosis, Pulmonary / pathology
  • Tomography, X-Ray Computed