Abstract
Erythropoietin (Epo) was measured by enzyme-linked immunosorbent assay in 80 cerebrospinal fluid (CSF) samples to determine whether Epo is present in the CSF of infants, CSF Epo concentrations correlate with age, and CSF Epo concentrations correlate with Epo therapy. Epo was present in the CSF of normal neonates. CSF Epo concentrations correlated negatively with increasing age. Recombinant Epo therapy did not affect CSF Epo concentrations, although values ranged somewhat higher in this group.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Adult
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Aging / cerebrospinal fluid
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Child
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Child, Preschool
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Enzyme-Linked Immunosorbent Assay
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Erythropoietin / cerebrospinal fluid*
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Erythropoietin / therapeutic use
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Gestational Age
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Humans
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Infant
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Infant, Newborn / cerebrospinal fluid*
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Infant, Premature / cerebrospinal fluid*
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Middle Aged
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Recombinant Proteins / therapeutic use
Substances
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Recombinant Proteins
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Erythropoietin