Efficacy of doramectin against intestinal nematodes and sarcoptic manage mites in naturally infected swine

J Vet Med Sci. 1997 Feb;59(2):129-32. doi: 10.1292/jvms.59.129.

Abstract

Endectocidal efficacy of doramectin administered intramuscularly at a dosage of 300 micrograms/kg was evaluated in 464 pigs naturally infected with intestinal nematodes or mange mites on 14 commercial farms in Japan. By doramectin treatment, fecal egg counts were reduced > 99% for Ascaris suum, Strongyloides ransomi, Oesophagostomum dentatum, and Trichuris suis; worm counts of T. suis and mite counts of Sarcoptes scabiei reduced 90.1% on Day 21 and 99.5% on Day 28 following treatment, respectively.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Animals
  • Anthelmintics / administration & dosage
  • Anthelmintics / therapeutic use*
  • Ascariasis / drug therapy
  • Ascariasis / veterinary
  • Ascaris suum / isolation & purification
  • Feces / parasitology
  • Female
  • Injections, Intravenous / veterinary
  • Intestinal Diseases, Parasitic / drug therapy
  • Intestinal Diseases, Parasitic / veterinary*
  • Ivermectin / administration & dosage
  • Ivermectin / analogs & derivatives*
  • Ivermectin / therapeutic use
  • Nematode Infections / drug therapy
  • Nematode Infections / veterinary*
  • Oesophagostomiasis / drug therapy
  • Oesophagostomiasis / veterinary
  • Oesophagostomum / isolation & purification
  • Parasite Egg Count / veterinary
  • Scabies / drug therapy
  • Scabies / veterinary*
  • Skin / parasitology
  • Strongyloides / isolation & purification
  • Strongyloidiasis / drug therapy
  • Strongyloidiasis / veterinary
  • Swine
  • Swine Diseases / drug therapy*
  • Time Factors
  • Trichuriasis / drug therapy
  • Trichuriasis / veterinary
  • Trichuris / isolation & purification

Substances

  • Anthelmintics
  • Ivermectin
  • doramectin