Abstract
FKBP-rapamycin associated protein (FRAP) is a phosphatidylinositol kinase (PIK)-related kinase implicated in the inhibition of progression through G1 of the cell cycle. The PIK-related kinases are a growing family of proteins involved in cell-cycle checkpoints, DNA repair and recombination. We have mapped the human FRAP gene to chromosome 1p36.2, a region consistently deleted in neuroblastomas.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Base Sequence
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Carrier Proteins / genetics
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Chromosome Mapping*
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Chromosomes, Human, Pair 1*
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Humans
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Immunophilins*
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In Situ Hybridization, Fluorescence
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Molecular Sequence Data
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Phosphotransferases (Alcohol Group Acceptor)*
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TOR Serine-Threonine Kinases
Substances
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Carrier Proteins
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Phosphotransferases (Alcohol Group Acceptor)
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MTOR protein, human
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TOR Serine-Threonine Kinases
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Immunophilins