Locoregional relapse following curative resection (= R0) of gastrointestinal cancer occurs in 30% (colorectal carcinoma) and up to 70% (ductal pancreatic cancer) of patients. A potential, complete removal of a tumor recurrence can be achieved, in particular, in the case of colorectal carcinoma. For these tumors and all their locations (loco-regional, metachronic liver and lung metastasis), 5-year survival rates can amount up to 40%. The survival rates of our own patients are presented.