The TEL gene contributes to the pathogenesis of myeloid and lymphoid leukemias by diverse molecular genetic mechanisms

Curr Top Microbiol Immunol. 1997:220:67-79. doi: 10.1007/978-3-642-60479-9_5.
No abstract available

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Adult
  • Amino Acid Sequence
  • Cell Transformation, Neoplastic / genetics*
  • Child
  • Chromosomes, Human, Pair 12 / genetics
  • Chromosomes, Human, Pair 12 / ultrastructure
  • Cloning, Molecular
  • Core Binding Factor Alpha 2 Subunit
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / physiology*
  • ETS Translocation Variant 6 Protein
  • Gene Deletion
  • Gene Expression Regulation, Leukemic*
  • Genes, abl
  • Helix-Loop-Helix Motifs / genetics
  • Humans
  • Leukemia / genetics*
  • Leukemia / pathology
  • Leukemia, Myelomonocytic, Chronic / genetics
  • Leukemia, Myelomonocytic, Chronic / pathology
  • Models, Genetic
  • Molecular Sequence Data
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / physiology*
  • Oncogene Proteins, Fusion / genetics
  • Oncogene Proteins, Fusion / physiology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • Proto-Oncogene Proteins c-ets
  • Proto-Oncogene Proteins*
  • Receptor, Platelet-Derived Growth Factor beta
  • Receptors, Platelet-Derived Growth Factor / genetics
  • Repressor Proteins*
  • Sequence Alignment
  • Sequence Homology, Amino Acid
  • Transcription Factors / genetics
  • Transcription Factors / physiology*
  • Translocation, Genetic

Substances

  • Core Binding Factor Alpha 2 Subunit
  • DNA-Binding Proteins
  • Neoplasm Proteins
  • Oncogene Proteins, Fusion
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-ets
  • Repressor Proteins
  • Transcription Factors
  • Receptor, Platelet-Derived Growth Factor beta
  • Receptors, Platelet-Derived Growth Factor