Patterns of content, contextual, and working memory impairments in schizophrenia and nonamnesic alcoholism

Neuropsychology. 1997 Apr;11(2):195-206. doi: 10.1037//0894-4105.11.2.195.

Abstract

This study used tests of content memory (item recognition of words and abstract designs), context memory (order recognition of verbal and nonverbal items), and working memory (recognition at a short retention interval) to examine patterns of performance in 27 schizophrenic patients, 52 chronic alcoholic patients, and 66 healthy control participants. When performance was age- and IQ-adjusted the schizophrenia group was significantly impaired in item and order recognition of verbal and nonverbal material; the alcoholic group was impaired only in order recognition for both material types. Item- and order-recognition deficits in the schizophrenia group were greatest at the shortest retention intervals, a pattern previously observed in patients with Parkinson's disease, suggesting a prominence of a working memory deficit in schizophrenia.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Alcoholism / psychology*
  • Female
  • Humans
  • Language*
  • Male
  • Memory / physiology*
  • Middle Aged
  • Schizophrenic Psychology*