Coexistence of a graft with the preserved native liver in auxiliary partial orthotopic liver transplantation from a living donor for ornithine transcarbamylase deficiency

Transplantation. 1997 Apr 15;63(7):1026-8. doi: 10.1097/00007890-199704150-00021.

Abstract

Background: Auxiliary partial orthotopic liver transplantation (APOLT) has recently been performed in patients with noncirrhotic metabolic liver diseases. However, long-term outcomes for the preserved native liver and the transplanted liver graft have not been clearly established yet.

Methods: The recipient was a 36-month-old girl with ornithine transcarbamylase deficiency. She underwent APOLT, using her father's left lateral segment.

Results: Liver function was normalized soon after APOLT and the patient was able to ingest a normal diet without medication. Coexistence of the well-functioning native liver and graft was demonstrated in a computed tomography scan, Doppler ultrasonography, scintigraphy, and histological examination, during a relatively long-term follow-up period.

Conclusions: APOLT seems to be most useful for the treatment of noncirrhotic metabolic liver diseases.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biopsy
  • Child, Preschool
  • Female
  • Humans
  • Liver / diagnostic imaging
  • Liver / pathology
  • Liver / physiology*
  • Liver Transplantation / diagnostic imaging
  • Liver Transplantation / methods
  • Liver Transplantation / pathology
  • Liver Transplantation / physiology*
  • Ornithine Carbamoyltransferase Deficiency Disease*
  • Radiography