Human chagasic disease is not associated with an antiheart humoral response

Am J Cardiol. 1997 Apr 15;79(8):1135-7. doi: 10.1016/s0002-9149(97)00065-9.

Abstract

An inflammatory cardiomyopathy occurs in humans with chronic Trypanosoma cruzi infection (Chagas' disease). This study finds that T. cruzi infection is not associated with the production of cardiac-specific autoantibodies in humans with cardiac manifestations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Animals
  • Antigens, Protozoan / blood*
  • Chagas Cardiomyopathy / immunology*
  • Chagas Disease / immunology*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Fluorescent Antibody Technique, Indirect
  • Humans
  • Male
  • Middle Aged
  • Myocardium / immunology*
  • Myosins / immunology*

Substances

  • Antigens, Protozoan
  • Myosins