Inhibition of CD28-B7 T-cell costimulatory activation pathway affects intragraft cytokine and growth factor expression in chronic renal allograft rejection

Transplant Proc. 1997 Feb-Mar;29(1-2):1038. doi: 10.1016/s0041-1345(96)00359-4.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Abatacept
  • Animals
  • Antigens, CD
  • Antigens, Differentiation / therapeutic use
  • B7-1 Antigen / physiology*
  • CD28 Antigens / physiology*
  • CTLA-4 Antigen
  • Cyclosporine / therapeutic use
  • Cytokines / biosynthesis*
  • Graft Rejection / immunology*
  • Graft Rejection / therapy
  • Growth Substances / biosynthesis*
  • Immunoconjugates*
  • Immunosuppression Therapy / methods
  • Kidney Transplantation / immunology*
  • Lymphocyte Activation
  • Rats
  • Rats, Inbred F344
  • Rats, Inbred Lew
  • T-Lymphocytes / immunology*
  • Time Factors
  • Transplantation, Homologous

Substances

  • Antigens, CD
  • Antigens, Differentiation
  • B7-1 Antigen
  • CD28 Antigens
  • CTLA-4 Antigen
  • Cytokines
  • Growth Substances
  • Immunoconjugates
  • Abatacept
  • Cyclosporine