Expression of a negative dominant mutant of human p55 tumor necrosis factor-receptor inhibits TNF and monocyte-induced activation in porcine aortic endothelial cells

Transplant Proc. 1997 Feb-Mar;29(1-2):882. doi: 10.1016/s0041-1345(96)00186-8.

Authors

D M Stroka¹, J T Cooper, C Brostjan, M T Millan, D J Goodman, C J Wrighton, F H Bach, C Ferran

Affiliation

¹ Sandoz Center for Immunobiology, Deaconess Hospital, Harvard Medical School, Boston, MA 02215, USA.

PMID: 9123566
DOI: 10.1016/s0041-1345(96)00186-8

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antigens, CD / biosynthesis*
Antigens, CD / genetics
Antigens, CD / physiology
Aorta
Cells, Cultured
Endothelium, Vascular / drug effects
Endothelium, Vascular / physiology*
Genes, Dominant
Graft Survival
Humans
Monocytes / physiology*
Receptors, Tumor Necrosis Factor / biosynthesis*
Receptors, Tumor Necrosis Factor / genetics
Receptors, Tumor Necrosis Factor / physiology
Receptors, Tumor Necrosis Factor, Type I
Recombinant Proteins / biosynthesis
Swine
Transfection
Transplantation, Heterologous
Tumor Necrosis Factor-alpha / pharmacology*

Substances

Antigens, CD
Receptors, Tumor Necrosis Factor
Receptors, Tumor Necrosis Factor, Type I
Recombinant Proteins
Tumor Necrosis Factor-alpha