Abstract
Two months after an osteosynthesis of a Maisonneuve-fracture a 45-year-old patient developed a thrombosis of the deep veins on the side of the fracture. Subsequent to two days of lysis with Streptokinase a rupture of the liver occurred and was treated by hemihepatectomy. A traumatic event or a tumor could be excluded as reason for the rupture. Therefore a rupture of the liver due to the application of Streptokinase has to be assumed.
MeSH terms
-
Chemical and Drug Induced Liver Injury*
-
Fatal Outcome
-
Female
-
Foot Injuries / surgery*
-
Fracture Fixation, Internal*
-
Humans
-
Liver / pathology
-
Liver Diseases / pathology
-
Middle Aged
-
Postoperative Complications / chemically induced*
-
Postoperative Complications / drug therapy
-
Postoperative Complications / pathology
-
Rupture, Spontaneous
-
Streptokinase / administration & dosage
-
Streptokinase / adverse effects*
-
Thrombolytic Therapy*
-
Thrombophlebitis / drug therapy*