Cytologic features of pulmonary metastasis from a granulosa cell tumor diagnosed by fine-needle aspiration: a case report

Diagn Cytopathol. 1997 Apr;16(4):341-4. doi: 10.1002/(sici)1097-0339(199704)16:4<341::aid-dc7>3.0.co;2-g.

Abstract

We report on a case of a granulosa cell tumor of the ovary metastatic to the lung and diagnosed by fine-needle aspiration. The patient was a 70-yr-old woman who was diagnosed with a granulosa cell tumor of the ovary 17 yr previously. She subsequently developed abdominal metastases and received several cycles of chemotherapy. A 0.5-cm right upper lobe pulmonary nodule was found on a routine chest radiograph and subsequent computerized tomography scan. Aspiration cytology of this pulmonary nodule demonstrated small, relatively uniform neoplastic cells with nuclear grooves and indentations consistent with a granulosa cell tumor. The differential diagnosis of granulosa cell tumors from other metastatic and pulmonary lesions is reviewed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy, Needle
  • Female
  • Granulosa Cell Tumor / diagnosis
  • Granulosa Cell Tumor / metabolism*
  • Humans
  • Lung / pathology*
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / secondary*
  • Neoplasm Metastasis
  • Ovarian Neoplasms / diagnosis
  • Ovarian Neoplasms / pathology*