Abstract
The authors report the treatment results of 89 children with renal tumors (excluding carcinoma) seen from 1988 to 1992, 71 (79.8%) with favorable-histology Wilms' tumor (survival 86%) and 18 (20.2%) with unfavorable histology, including anaplastic nephroblastoma, clear-cell sarcoma, and rhabdoid tumor (survival 61%). Preoperative chemotherapy (ChT) was given to 46 patients (survival 84%); none was given to 43 with either tumors in the 1st year of life, massive hematuria, or tumor growth during ChT (survival 78%). There were 3 tumor ruptures in the latter group compared to 1 in the former group.
MeSH terms
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Chemotherapy, Adjuvant
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Child
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Child, Preschool
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Combined Modality Therapy
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Female
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Follow-Up Studies
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Humans
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Infant
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Kidney / pathology
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Kidney Neoplasms / drug therapy
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Kidney Neoplasms / mortality
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Kidney Neoplasms / pathology
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Kidney Neoplasms / surgery*
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Male
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Neoplasm Staging
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Nephrectomy*
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Rhabdoid Tumor / drug therapy
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Rhabdoid Tumor / mortality
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Rhabdoid Tumor / pathology
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Rhabdoid Tumor / surgery*
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Sarcoma, Clear Cell / drug therapy
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Sarcoma, Clear Cell / mortality
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Sarcoma, Clear Cell / pathology
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Sarcoma, Clear Cell / surgery*
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Survival Rate
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Wilms Tumor / drug therapy
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Wilms Tumor / mortality
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Wilms Tumor / pathology
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Wilms Tumor / surgery*