Abstract
Prior irradiation to a site is a relative and often absolute contraindication to further irradiation because the tolerance dose of normal tissues is usually exceeded and therefore the risk of serious long-term side-effects is high. This case report describes radical salvage chemoradiation for an esophageal carcinoma in a patient who had prior high-dose neck and chest wall irradiation for the management of a breast cancer 19 years previously.
MeSH terms
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Adenocarcinoma / diagnostic imaging
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Adenocarcinoma / drug therapy
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Adenocarcinoma / radiotherapy*
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Breast Neoplasms / diagnostic imaging
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Breast Neoplasms / drug therapy
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Breast Neoplasms / radiotherapy*
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Carcinoma, Squamous Cell / diagnostic imaging
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Carcinoma, Squamous Cell / drug therapy
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Carcinoma, Squamous Cell / radiotherapy*
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Cisplatin / administration & dosage
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Combined Modality Therapy
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Esophageal Neoplasms / diagnostic imaging
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Esophageal Neoplasms / drug therapy
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Esophageal Neoplasms / radiotherapy*
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Esophagus / radiation effects*
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Female
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Fluorouracil / administration & dosage
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Follow-Up Studies
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Humans
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Middle Aged
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Neoplasm Recurrence, Local / diagnostic imaging
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Neoplasm Recurrence, Local / drug therapy
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Neoplasm Recurrence, Local / radiotherapy*
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Neoplasms, Radiation-Induced / diagnostic imaging
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Neoplasms, Radiation-Induced / drug therapy
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Neoplasms, Radiation-Induced / radiotherapy*
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Neoplasms, Second Primary / diagnostic imaging
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Neoplasms, Second Primary / drug therapy
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Neoplasms, Second Primary / radiotherapy*
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Salvage Therapy
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Tomography, X-Ray Computed
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Treatment Outcome